Today, the market of digital imaging systems using a CMOS image sensor (CIS) are explosively grown due to a demand on the miniaturized, low-power, low-cost solutions for the surveillance systems as well as mobile/handheld devices. Due to the capability of integration with the circuitry and processing unit, CIS is the most powerful technology for the automotive, surveillance systems, wireless image sensor network which requires the integrated functions or performance enhancement schemes. A CMOS fingerprint sensor which is another type of image sensor providing a fingerprint image becomes crucial in the internet commerce, data security, and passport control. Among the biometric technologies, fingerprint is one of the most representative methods and has long been used as a means of identification. Furthermore, fingerprinting is adaptable to various portable devices, and thus fingerprint identification systems can potentially be implemented in a miniaturized system. Our group has been developed and demonstrated three types of prototype CMOS image sensors and two CMOS fingerprint sensors as follows.